| 张高荣1,2, 黄锡山2, 黄 艳2, 赖红芳1, 王爱娟1, 李 俊2* |
| 1. 河池学院 化学与生物工程学院, 微生物及植物资源开发利用广西高校重点实验室, 广西 宜州 546300;2. 广西师范大学 化学与药学学院, 省部共建药用资源化学与药物分子工程国家重点实验室, 广西 桂林 541000 |
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| 摘要: |
| 为研究刺桑(Taxotrophis ilicifolia)皮正丁醇部位的化学成分,该研究采用硅胶、ODS、Sephadex LH-20、反相半制备高效液相等色谱法对刺桑皮正丁醇萃取部位进行分离纯化,并综合理化性质及波谱数据鉴定其化合物的结构。结果表明:从刺桑皮正丁醇萃取物中分离得到16个化合物,分别鉴定为icariside E5(1)、裂环异落叶松脂醇-9-O-β-吡喃葡萄糖苷(2)、2,4,6-三甲氧基苯酚-1-O-β-D-葡萄糖苷(3)、9-O-β-glucopyranosyl trans-cinnamyl alcohol(4)、3,4,5-三甲氧基苯酚-1-O-β-呋喃芹糖基-(1″→6')-β-吡喃葡萄糖苷(5)、3-羟基-4,5-二甲氧基苯酚-β-D-吡喃葡萄糖苷(6)、2,6-二甲氧基-4-羟基苯酚-1-O-β-D-吡喃葡萄糖苷(7)、isotachioside(8)、ficuscarpanoside A(9)、uridine(10)、methyl syringate 4-O-β-D-glucopyranoside(11)、3,4,5-三甲氧基苯酚-β-D-吡喃葡萄糖苷(12)、木犀草素(13)、人参皂苷Rg1(14)、(+)-lyonirenisol-3α-O-β-D-glucopyranoside(15)、myricetin 3-neohesperidoside(16)。所有化合物均为首次从该属植物中分离得到。 |
| 关键词: 刺桑, 化学成分, icariside E5, 裂环异落叶松脂醇-9-O-β-吡喃葡萄糖苷, 人参皂苷Rg1 |
| DOI：10.11931/guihaia.gxzw202112055 |
| 分类号:Q946 |
| 文章编号:1000-3142(2023)01-0165-09 |
| 基金项目:国家自然科学基金(216620040); 河池学院高层次人才科研项目(2021GCC018); 河池学院科研项目(2020XJYB007); 广西高校中青年教师科研基础能力提升项目(2022KY0611)。 |
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| Chemical constituents from the bark of n-BuOH fraction of Taxotrophis ilicifolia |
| ZHANG Gaorong1, 2, HUANG Xishan2, HUANG Yan2, LAI Hongfang1, Wang Aijuan1, LI Jun2 |
| Hospital of Traditional Chinese Medicine, Qinzhou 535099, China |
| Abstract: |
| To study the chemical constituents from the n-BuOH part of the bark of Taxotrophis ilicifolia, sixteen compounds were isolated and purified from the n-BuOH part of the bark of T. ilicifolia by means of various column chromatographic techniques, including silica gel, ODS, Sephadex LH-20 and semi-preparative RP-HPLC. The structures of the isolates were identified by physiochemical properties and spectral data. The results were as follows: The compounds were identified as icariside E5(1), secoisolariciresinol 9-O-β-glucopyranoside(2), 2,4,6-trimethoxyphenol-1-O-β-D-glycoside(3),9-O-β-glucopyranosyl trans-cinnamyl alcohol(4), 3,4,5-trimethoxyphenyl-1-O-β-apiofuranosyl-(1″→6')-β-glucopyranoside(5),3-hydroxy-4,5-dimethoxyphenyl-β-D-glucopyranoside(6), 2,6-dimethoxy-4- hydroxyphenol-1-O-β-D-glucopyranoside(7), isotachioside(8), ficuscarpanoside A(9), uridine(10), methyl syringate 4-O-β-D-glucopyranoside(11), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside(12), luteolin(13), ginsenoside Rg1(14),(+)-lyonirenisol-3α-O-β-D-glucopyranoside(15), myricetin 3-neohesperidoside(16). All compounds were isolated from plants of Taxotrophis for the first time. |
| Key words: Taxotrophis ilicifolia, chemical constituents, icariside E5, secoisolariciresinol 9-O-β-glucopyranoside, ginsenoside Rg1 |
刺桑皮正丁醇部位化学成分研究.pdf
