韩丹翔——中国科学院水生生物研究所博士

韩丹翔，女，博士，研究员。中国科学院水生生物研究所研究员，**计划入选者。

教育及工作经历： 　　

1997-2001 武汉大学 药学专业 理学学士 　　

2001-2006 中国科学院水生生物研究所 水生生物学 理学博士 　　

2006-2010 博士后研究员, 美国亚利桑那州立大学 　　

2010-2014 助理研究教授, 美国亚利桑那州立大学

学术兼职：

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研究方向：

藻类生物学与藻类生物技术。研究内容涉及藻类生理生化及分子细胞生物学，

1）油脂生物合成、调控及储存机制。

2）类胡萝卜素等高附加值产品的生物合成。

3）微藻抗逆生物学。

4）微藻系统代谢工程及合成生物学。

承担科研项目情况：

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科研成果：

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发明专利：

1、PCT on Novel Pseudochlorococcum Species and Uses Therefore

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发表英文论文：

1.Guanqun Chen, Baobei Wang, Danxiang Han, Milton Sommerfeld, Yinghua Lu, Feng Chen andQiang Hu (2015) Molecular mechanisms of the coordination between astaxanthin and fatty acid biosynthesis in Haematococcus pluvialis(Chlorophyceae). The Plant Journal 81, 95-107 

2. Baobei Wang, Zhen Zhang, Qiang Hu, Milton Sommerfeld, Yinghua Lu andDanxiang Han (2014) Cellular capacities for high-light acclimation developed in life cycle of the green alga Haematococcuspluvialis. PLoS One DOI: 10.1371/journal.pone.0106679 

3.Yunho Gwak, Yong-sic Hwang, Baobei Wang, Minju Kim, JooyeonJeong, Choul-Gyun Lee, Qiang Hu, Danxiang Han & EonSeonJin (2014) Comparative analyses of lipidomes and transcriptomes reveals a concerted action of multiple defensive systems against photooxidative stress in Haematococcus pluvialis. Journal of Experimental Botany 65: 4317-4334  (Co-Corresponding Author) 

4. Jing Li, Danxiang Han, Dongmei Wang, Kang Ning, Jing Jia, Li Wei, Xiaoyan Jing, Shi Huang, Jie Chen,Yantao Li, Qiang Hu and Jian Xu. (2014) Choreography of transcriptomes and lipidomes in Nannochloropsis reveals the mechanisms of oleaginousness in microalgae. Plant Cell, 26(4): 1645-1665 

5.Wang, D., Ning, K., Li, J., Han, D., Wang H., et al (2014) Nannochloropsisphylogenome revealed evolution of microalgal oleaginous traits. Plos Genetics 10: e1004094 

6.Han, D., Li, Y. & Hu, Q. (2013) Biology and commercial aspects ofHaematococcus pluvialis. pp. 388-405. In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2^nd edition, Wiley-Blackwell, West Sussex, UK. 

7.Han, D., Deng, Z., Lu, F. & Hu, Z. (2013) Biology and biotechnology of edibleNostoc, pp. 433-444.In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2^nd edition, Wiley-Blackwell, West Sussex, UK. 

8.Li, Y., Chen, W., Shen, H., Han, D., Li, Y., Jones, H., Timlin JA.& Hu, Q. (2013) Basic culturing and analytical measurement techniques, pp.37-68. In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2^nd edition, Blackwell Science Ltd., Oxford, UK. 

9.Li, Y., Han, D., Yoon, K., Zhu, S., Sommerfeld, M. & Hu, Q. (2013) Molecular and cellular mechanisms for lipid synthesis and accumulation in microalgae: biotechnological implication, pp. 545-565.In: Richmond, A. & Hu, Q. (eds.): Handbook of Microalgal Culture, 2^nd edition, Wiley-Blackwell, West Sussex, UK. 

10.Han, D., Li, Y. & Hu, Q. (2013) Astaxanthin in microalgae: Biosynthesis pathways, regulation and biotechnological applications. Algae 28: 131-147 

11.Yoon, K.S., Han, D., Li, Y. Sommerfeld, M. & Hu Q. (2012) Phospholipid:diacylglycerolacyltransferase is a multifunctional enzyme involved in membrane lipid turnover and degradation while synthesizing triacylglycerol in the unicellular green microalga Chlamydomonasreinhardtii. Plant Cell 24: 3708-24 (Co-First Author) 

12.Wang, J., Han, D., Sommerfeld, M. & Hu, Q. (2012) Effect of initial biomass density on growth and astaxanthin production of Haematococcuspluvialis in an outdoor photobioreactor.Journal of Applied Phycology DOI: 10.1007/S10811-012-9859-4 

13.Han, D., Wang, J., Sommerfeld, M. & Hu, Q. (2012) Susceptibility and protective mechanisms of motile and non-motile cells of Haematococcuspluvialis(Chlorophyceae) to photooxidative stress.Journal of Phycology 48:693-705 

14.Collins, A., Jones, H., Han, D., Hu, Beechem, T. &Timlin, J. (2011) Carotenoid distribution in living cells of Haematococcuspluvialis (Chlorophyceae).Plos ONE 6: e24302 DOI: 10.1371/journal.pone.0024302 

15.Li, Y., Han, D., Sommerfeld, M. & Hu, Q. (2011) Photosynthetic carbon partitioning and lipid production in the oleaginous microalga Pseudochlorococcum sp. (Chlorophyceae) under nitrogen-limited conditions.Bioresource Technology 102: 123-9 

16.Li, Y., Han, D., Hu, G., Sommerfeld, M. & Hu, Q. (2010) Inhibition of starch synthesis results in overproduction of lipids in starchless mutants ofChlamydomonasreinhardtii.Biotechnology & Bioengineering, 107: 258-68 

17.Li, Y., Han, D., Hu, G., Dauville, D., Sommerfeld, M., Ball, S. & Hu, Q (2009) Chlamydomonasstarchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol. Metabolic Engineering 12: 387-91 

18.Han, D., Fan, Y. & Hu, Z. (2009) An evaluation of four phylogenetic markers inNostoc: Implications for cyanobacterial phylogenetic studies at the intrageneric level.Current Microbiology 58: 170-176 

       发表中文论文：

       1 念珠藻属植物的应用研究  韩丹翔; 胡征宇; 刘永定  中国藻类学会第十一次学术讨论会论文摘要集  2001-11-01  中国会议     

2 蓝藻念珠藻属系统发育和分子进化研究  韩丹翔  中国科学院研究生院（水生生物研究所）  2006-06-01  博士 

荣誉奖励：

1、2014年入选中国科学院**计划。